Widespread intronic polyadenylation diversifies immune cell transcriptomes

Alternative cleavage and polyadenylation (ApA) is known to alter untranslated region (3ʹUTR) length but can also recognize intronic polyadenylation (IpA) signals to generate transcripts that lose part or all of the coding region. We analyzed 46 3ʹ-seq and RNA-seq profiles from normal human tissues,...

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Detalles Bibliográficos
Autores principales: Singh, Irtisha, Lee, Shih-Han, Sperling, Adam S., Samur, Mehmet K., Tai, Yu-Tzu, Fulciniti, Mariateresa, Munshi, Nikhil C., Mayr, Christine, Leslie, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928244/
https://www.ncbi.nlm.nih.gov/pubmed/29712909
http://dx.doi.org/10.1038/s41467-018-04112-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928244/
https://www.ncbi.nlm.nih.gov/pubmed/29712909
http://dx.doi.org/10.1038/s41467-018-04112-z

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