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Nobiletin attenuates neurotoxic mitochondrial calcium overload through K(+) influx and ΔΨ(m) across mitochondrial inner membrane

Mitochondrial calcium overload is a crucial event in determining the fate of neuronal cell survival and death, implicated in pathogenesis of neurodegenerative diseases. One of the driving forces of calcium influx into mitochondria is mitochondria membrane potential (ΔΨ(m)). Therefore, pharmacologica...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyung, Amarsanaa, Khulan, Wu, Jinji, Jeon, Sang-Chan, Cui, Yanji, Jung, Sung-Cherl, Park, Deok-Bae, Kim, Se-Jae, Han, Sang-Heon, Kim, Hyun-Wook, Rhyu, Im Joo, Eun, Su-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928344/
https://www.ncbi.nlm.nih.gov/pubmed/29719453
http://dx.doi.org/10.4196/kjpp.2018.22.3.311