The Versatility of Framework Regions of Chicken V(H) and V(L) to Mutations

To identify the interchangeability of V(H) and V(L) framework region (FR) residues, we artificially introduced random mutations at all residue positions in a chicken monoclonal antibody, which has only one functional V(H) and V(λ) gene. When we classified the amino acids into 5 groups by their physi...

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Detalles Bibliográficos
Autores principales: Shin, Jung Won, Kim, Sang Il, Yoon, Aerin, Jin, Junyeong, Park, Hyung Bae, Kim, Hyori, Chung, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928418/
https://www.ncbi.nlm.nih.gov/pubmed/29732232
http://dx.doi.org/10.4110/in.2018.18.e3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928418/
https://www.ncbi.nlm.nih.gov/pubmed/29732232
http://dx.doi.org/10.4110/in.2018.18.e3

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