Mutations Alter RNA-Mediated Conversion of Human Prions

[Image: see text] Prion diseases are connected with self-replication and self-propagation of misfolded proteins. The rate-limiting factor is the formation of the initial seed. We have recently studied the early stages in the conversion between functional PrP(C) and the infectious scrapie PrP(SC) for...

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Detalles Bibliográficos
Autores principales: Alred, Erik J., Lodangco, Izra, Gallaher, Jennifer, Hansmann, Ulrich H.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928492/
https://www.ncbi.nlm.nih.gov/pubmed/29732450
http://dx.doi.org/10.1021/acsomega.7b02007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928492/
https://www.ncbi.nlm.nih.gov/pubmed/29732450
http://dx.doi.org/10.1021/acsomega.7b02007

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