Cargando…

TNF-α and RANKL promote osteoclastogenesis by upregulating RANK via the NF-κB pathway

Although tumor necrosis factor alpha (TNF-α) is known to serve a critical role in the pathogenesis of inflammatory osteolysis, the exact mechanisms underlying the effects of TNF-α on osteoclast recruitment and differentiation remain unclear. To investigate the mechanisms by which TNF-α influences os...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Gang, Li, Fangfei, Li, Xiaoming, Wang, Zheng-Guo, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928634/
https://www.ncbi.nlm.nih.gov/pubmed/29512766
http://dx.doi.org/10.3892/mmr.2018.8698