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Therapeutic window for YC-1 following glutamate-induced neuronal damage and transient focal cerebral ischemia

3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1), has been demonstrated to inhibit platelet aggregation, vascular contraction and hypoxia-inducible factor 1 activity in vitro and in vivo. The present study investigated the neuroprotective efficacy of YC-1 in cultured neurons exposed to glutamat...

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Detalles Bibliográficos
Autores principales: Tai, Shih-Huang, Lee, Wei-Ting, Lee, Ai-Chiang, Lin, Yu-Wen, Hung, Hsin-Yi, Huang, Sheng-Yang, Wu, Tian-Shung, Lee, E-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928635/
https://www.ncbi.nlm.nih.gov/pubmed/29512783
http://dx.doi.org/10.3892/mmr.2018.8660