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Therapeutic window for YC-1 following glutamate-induced neuronal damage and transient focal cerebral ischemia
3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1), has been demonstrated to inhibit platelet aggregation, vascular contraction and hypoxia-inducible factor 1 activity in vitro and in vivo. The present study investigated the neuroprotective efficacy of YC-1 in cultured neurons exposed to glutamat...
Autores principales: | Tai, Shih-Huang, Lee, Wei-Ting, Lee, Ai-Chiang, Lin, Yu-Wen, Hung, Hsin-Yi, Huang, Sheng-Yang, Wu, Tian-Shung, Lee, E-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928635/ https://www.ncbi.nlm.nih.gov/pubmed/29512783 http://dx.doi.org/10.3892/mmr.2018.8660 |
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