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Dexmedetomidine attenuates H(2)O(2)-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways

Dexmedetomidine (DEX), an α2 adrenoceptor agonist, has sedative and analgesic properties and myocardial protective effects. However, the mechanism underlying the protective effects of DEX on the myocardium remain unclear. The present study aimed to determine whether DEX serves an important role on c...

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Detalles Bibliográficos
Autores principales: Liu, Xue-Ru, Li, Tao, Cao, Lu, Yu, Yi-Yan, Chen, Lin-Lin, Fan, Xue-Hui, Yang, Bin-Bin, Tan, Xiao-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928682/
https://www.ncbi.nlm.nih.gov/pubmed/29568958
http://dx.doi.org/10.3892/mmr.2018.8751