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Dexmedetomidine attenuates H(2)O(2)-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways
Dexmedetomidine (DEX), an α2 adrenoceptor agonist, has sedative and analgesic properties and myocardial protective effects. However, the mechanism underlying the protective effects of DEX on the myocardium remain unclear. The present study aimed to determine whether DEX serves an important role on c...
Autores principales: | Liu, Xue-Ru, Li, Tao, Cao, Lu, Yu, Yi-Yan, Chen, Lin-Lin, Fan, Xue-Hui, Yang, Bin-Bin, Tan, Xiao-Qiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928682/ https://www.ncbi.nlm.nih.gov/pubmed/29568958 http://dx.doi.org/10.3892/mmr.2018.8751 |
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