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Inhibition of GluR Current in Microvilli of Sensory Neurons via Na(+)-Microdomain Coupling Among GluR, HCN Channel, and Na(+)/K(+) Pump

Glutamatergic dendritic EPSPs evoked in cortical pyramidal neurons are depressed by activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels expressed in dendritic spines. This depression has been attributed to shunting effects of HCN current (I(h)) on input resistance or I(h...

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Detalles Bibliográficos
Autores principales: Kawasaki, Yasuhiro, Saito, Mitsuru, Won, Jonghwa, Bae, Jin Young, Sato, Hajime, Toyoda, Hiroki, Kuramoto, Eriko, Kogo, Mikihiko, Tanaka, Takuma, Kaneko, Takeshi, Oh, Seog Bae, Bae, Yong Chul, Kang, Youngnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928758/
https://www.ncbi.nlm.nih.gov/pubmed/29740287
http://dx.doi.org/10.3389/fncel.2018.00113