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D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum

In mammals, D-Ser is synthesized by serine racemase (SR) and degraded by D-amino acid oxidase (DAO). D-Ser acts as an endogenous ligand for N-methyl-D-aspartate (NMDA)- and δ2 glutamate receptors, and is involved in brain functions such as learning and memory. Although SR homologs are highly conserv...

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Detalles Bibliográficos
Autores principales: Ito, Tomokazu, Hamauchi, Natsuki, Hagi, Taisuke, Morohashi, Naoya, Hemmi, Hisashi, Sato, Yukie G., Saito, Tamao, Yoshimura, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928759/
https://www.ncbi.nlm.nih.gov/pubmed/29740415
http://dx.doi.org/10.3389/fmicb.2018.00784