Cargando…

CAFs enhance paclitaxel resistance by inducing EMT through the IL-6/JAK2/STAT3 pathway

Carcinoma-associated fibroblasts (CAFs) are the major components of mesenchymal cells in the inflammatory tumor microenvironment. They are involved in epithelial-mesenchymal transition (EMT) and chemotherapy resistance by directly contacting with cancer cells or secretory cytokines. In the present s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Linlin, Zhang, Fang, Cui, Jian-Ying, Chen, Liang, Chen, Yue-Ting, Liu, Bo-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928760/
https://www.ncbi.nlm.nih.gov/pubmed/29565447
http://dx.doi.org/10.3892/or.2018.6311