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CAFs enhance paclitaxel resistance by inducing EMT through the IL-6/JAK2/STAT3 pathway
Carcinoma-associated fibroblasts (CAFs) are the major components of mesenchymal cells in the inflammatory tumor microenvironment. They are involved in epithelial-mesenchymal transition (EMT) and chemotherapy resistance by directly contacting with cancer cells or secretory cytokines. In the present s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928760/ https://www.ncbi.nlm.nih.gov/pubmed/29565447 http://dx.doi.org/10.3892/or.2018.6311 |