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Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life

Male sex hormones—androgens—regulate male physique development. Without androgen signaling, genetic males appear female. During puberty, increasing androgens harness the hair follicle’s unique regenerative ability to replace many tiny vellus hairs with larger, darker terminal hairs (e.g., beard). Fo...

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Detalles Bibliográficos
Autores principales: Miranda, Benjamin H., Charlesworth, Matthew R., Tobin, Desmond J., Sharpe, David T., Randall, Valerie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928870/
https://www.ncbi.nlm.nih.gov/pubmed/29046359
http://dx.doi.org/10.1096/fj.201700260RR