Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway

Protoporphyrin IX (PpIX) is an endogenous fluorescent molecule that selectively accumulates in cancer cells treated with the heme precursor 5-aminolevulinic acid (5-ALA). This cancer-specific accumulation of PpIX is used to distinguish tumor from normal tissues in fluorescence-guided surgery (FGS) a...

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Detalles Bibliográficos
Autores principales: Yoshioka, Ema, Chelakkot, Vipin Shankar, Licursi, Maria, Rutihinda, Suzette G, Som, Jayoti, Derwish, Leena, King, Justin J, Pongnopparat, Theerawat, Mearow, Karen, Larijani, Mani, Dorward, Ann M, Hirasawa, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928876/
https://www.ncbi.nlm.nih.gov/pubmed/29721068
http://dx.doi.org/10.7150/thno.22641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928876/
https://www.ncbi.nlm.nih.gov/pubmed/29721068
http://dx.doi.org/10.7150/thno.22641

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