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Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway
Protoporphyrin IX (PpIX) is an endogenous fluorescent molecule that selectively accumulates in cancer cells treated with the heme precursor 5-aminolevulinic acid (5-ALA). This cancer-specific accumulation of PpIX is used to distinguish tumor from normal tissues in fluorescence-guided surgery (FGS) a...
Autores principales: | Yoshioka, Ema, Chelakkot, Vipin Shankar, Licursi, Maria, Rutihinda, Suzette G, Som, Jayoti, Derwish, Leena, King, Justin J, Pongnopparat, Theerawat, Mearow, Karen, Larijani, Mani, Dorward, Ann M, Hirasawa, Kensuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928876/ https://www.ncbi.nlm.nih.gov/pubmed/29721068 http://dx.doi.org/10.7150/thno.22641 |
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