Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy

The therapy of non-small-cell lung cancer (NSCLC) is challenging because of poor prognosis. There are urgent demands for targeting anti-tumor drugs with reliable efficacy and clear pharmacokinetics. Methods: We designed and synthesized an active tumor-targeting prodrug for the precision therapy of N...

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Detalles Bibliográficos
Autores principales: Song, Xinyu, Han, Xiaoyue, Yu, Fabiao, Zhang, Xiaoyu, Chen, Lingxin, Lv, Changjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928882/
https://www.ncbi.nlm.nih.gov/pubmed/29721074
http://dx.doi.org/10.7150/thno.24041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928882/
https://www.ncbi.nlm.nih.gov/pubmed/29721074
http://dx.doi.org/10.7150/thno.24041

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