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Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy

Rationale: Treatment for Parkinson's disease (PD) is challenged by the presence of the blood-brain barrier (BBB) that significantly limits the effective drug concentration in a patient's brain for therapeutic response throughout various stages of PD. Curcumin holds the potential for α-synu...

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Detalles Bibliográficos
Autores principales: Zhang, Nisi, Yan, Fei, Liang, Xiaolong, Wu, Manxiang, Shen, Yuanyuan, Chen, Min, Xu, Yunxue, Zou, Guangyang, Jiang, Peng, Tang, Caiyun, Zheng, Hairong, Dai, Zhifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928888/
https://www.ncbi.nlm.nih.gov/pubmed/29721078
http://dx.doi.org/10.7150/thno.23734