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DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer

Background: Biomarkers predicting response to bevacizumab in breast cancer are still missing. Since epigenetic modifications can contribute to an aberrant regulation of angiogenesis and treatment resistance, we investigated the influence of DNA methylation patterns on bevacizumab efficacy. Methods:...

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Detalles Bibliográficos
Autores principales: Gampenrieder, Simon Peter, Rinnerthaler, Gabriel, Hackl, Hubert, Pulverer, Walter, Weinhaeusel, Andreas, Ilic, Suzana, Hufnagl, Clemens, Hauser-Kronberger, Cornelia, Egle, Alexander, Risch, Angela, Greil, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928889/
https://www.ncbi.nlm.nih.gov/pubmed/29721079
http://dx.doi.org/10.7150/thno.23544