Graphene oxide sensitizes cancer cells to chemotherapeutics by inducing early autophagy events, promoting nuclear trafficking and necrosis

Rationale: Cisplatin (CDDP) is a broad-spectrum anticancer drug but chemoresistance to CDDP impedes its wide use for cancer therapy. Autophagy is an event occurring in the cytoplasm and cytoplasmic LC3 puncta formation is a hallmark of autophagy. Graphene oxide (GO) is a nanomaterial that provokes a...

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Detalles Bibliográficos
Autores principales: Lin, Kuan-Chen, Lin, Mei-Wei, Hsu, Mu-Nung, Yu-Chen, Guan, Chao, Yu-Chan, Tuan, Hsing-Yu, Chiang, Chi-Shiun, Hu, Yu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928903/
https://www.ncbi.nlm.nih.gov/pubmed/29721093
http://dx.doi.org/10.7150/thno.24173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928903/
https://www.ncbi.nlm.nih.gov/pubmed/29721093
http://dx.doi.org/10.7150/thno.24173

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