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Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers

Purpose: To demonstrate the safety and feasibility of leveraging therapeutic antibodies for surgical imaging. Procedures: We conducted two phase I trials for anti-epidermal growth factor receptor antibodies cetuximab-IRDye800CW (n=12) and panitumumab-IRDye800CW (n=15). Adults with biopsy-confirmed h...

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Detalles Bibliográficos
Autores principales: Gao, Rebecca W., Teraphongphom, Nutte, de Boer, Esther, van den Berg, Nynke S., Divi, Vasu, Kaplan, Michael J., Oberhelman, Nicholas J., Hong, Steven S., Capes, Elissa, Colevas, A. Dimitrios, Warram, Jason M., Rosenthal, Eben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928904/
https://www.ncbi.nlm.nih.gov/pubmed/29721094
http://dx.doi.org/10.7150/thno.24487