Cargando…
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differin...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929158/ https://www.ncbi.nlm.nih.gov/pubmed/29641996 http://dx.doi.org/10.1016/j.celrep.2018.03.056 |