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Structural studies of crystalline forms of triamterene with carboxylic acid, GRAS and API molecules

Pharmaceutical salt solvates (dimethyl sulfoxide, DMSO) of the drug triamterene with the coformers acetic, succinic, adipic, pimelic, azelaic and nicotinic acid and ibuprofen are prepared by liquid-assisted grinding and solvent-evaporative crystallization. The modified ΔpK (a) rule as proposed by Cr...

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Detalles Bibliográficos
Autores principales: Rehman, Abida, Delori, Amit, Hughes, David S., Jones, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929377/
https://www.ncbi.nlm.nih.gov/pubmed/29755747
http://dx.doi.org/10.1107/S2052252518003317