Cargando…

Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions

Primary human colorectal tumors with a high stromal content have an increased capacity to metastasize. Cancer-associated fibroblasts (CAFs) promote metastasis, but the contribution of other stromal cell types is unclear. Here we searched for additional stromal cell types that contribute to aggressiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Trumpi, Kari, Frenkel, Nicola, Peters, Timo, Korthagen, Nicoline M., Jongen, Jennifer M.J., Raats, Daniëlle, van Grevenstein, Helma, Backes, Yara, Moons, Leon M., Lacle, Miangela M., Koster, Jan, Zwijnenburg, Danny, Borel Rinkes, Inne H.M., Kranenburg, Onno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929404/
https://www.ncbi.nlm.nih.gov/pubmed/29731961
http://dx.doi.org/10.18632/oncotarget.24626