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Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions

Primary human colorectal tumors with a high stromal content have an increased capacity to metastasize. Cancer-associated fibroblasts (CAFs) promote metastasis, but the contribution of other stromal cell types is unclear. Here we searched for additional stromal cell types that contribute to aggressiv...

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Detalles Bibliográficos
Autores principales: Trumpi, Kari, Frenkel, Nicola, Peters, Timo, Korthagen, Nicoline M., Jongen, Jennifer M.J., Raats, Daniëlle, van Grevenstein, Helma, Backes, Yara, Moons, Leon M., Lacle, Miangela M., Koster, Jan, Zwijnenburg, Danny, Borel Rinkes, Inne H.M., Kranenburg, Onno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929404/
https://www.ncbi.nlm.nih.gov/pubmed/29731961
http://dx.doi.org/10.18632/oncotarget.24626

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