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Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions
Primary human colorectal tumors with a high stromal content have an increased capacity to metastasize. Cancer-associated fibroblasts (CAFs) promote metastasis, but the contribution of other stromal cell types is unclear. Here we searched for additional stromal cell types that contribute to aggressiv...
Autores principales: | Trumpi, Kari, Frenkel, Nicola, Peters, Timo, Korthagen, Nicoline M., Jongen, Jennifer M.J., Raats, Daniëlle, van Grevenstein, Helma, Backes, Yara, Moons, Leon M., Lacle, Miangela M., Koster, Jan, Zwijnenburg, Danny, Borel Rinkes, Inne H.M., Kranenburg, Onno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929404/ https://www.ncbi.nlm.nih.gov/pubmed/29731961 http://dx.doi.org/10.18632/oncotarget.24626 |
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