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Mouse genetic background influences whether Hras(G12V) expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma
Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated pleomorphic sarcomas (UPS). To examine sarcoma-re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929423/ https://www.ncbi.nlm.nih.gov/pubmed/29731980 http://dx.doi.org/10.18632/oncotarget.24831 |