Mouse genetic background influences whether Hras(G12V) expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma

Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated pleomorphic sarcomas (UPS). To examine sarcoma-re...

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Detalles Bibliográficos
Autores principales: Brandt, Laura P., Albers, Joachim, Hejhal, Tomas, Pfundstein, Svende, Gonçalves, Ana Filipa, Catalano, Antonella, Wild, Peter J., Frew, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929423/
https://www.ncbi.nlm.nih.gov/pubmed/29731980
http://dx.doi.org/10.18632/oncotarget.24831

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