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Metal cofactor modulated folding and target recognition of HIV-1 NCp7

The HIV-1 nucleocapsid 7 (NCp7) plays crucial roles in multiple stages of HIV-1 life cycle, and its biological functions rely on the binding of zinc ions. Understanding the molecular mechanism of how the zinc ions modulate the conformational dynamics and functions of the NCp7 is essential for the dr...

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Detalles Bibliográficos
Autores principales: Ren, Weitong, Ji, Dongqing, Xu, Xiulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929515/
https://www.ncbi.nlm.nih.gov/pubmed/29715277
http://dx.doi.org/10.1371/journal.pone.0196662