Deciphering the binding behavior of flavonoids to the cyclin dependent kinase 6/cyclin D complex

Flavonoids, a class of natural compounds with variable phenolic structures, have been found to possess anti-cancer activities by modulating different enzymes and receptors like CDK6. To understand the binding behavior of flavonoids that inhibit the active CDK6, molecular dynamics (MD) simulations we...

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Detalles Bibliográficos
Autores principales: Zhang, Jingxiao, Zhang, Lilei, Xu, Yangcheng, Jiang, Shanshan, Shao, Yueyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929560/
https://www.ncbi.nlm.nih.gov/pubmed/29715320
http://dx.doi.org/10.1371/journal.pone.0196651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929560/
https://www.ncbi.nlm.nih.gov/pubmed/29715320
http://dx.doi.org/10.1371/journal.pone.0196651

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