The Cellular Response to Transcription-Blocking DNA Damage

In response to transcription-blocking DNA lesions such as those generated by UV irradiation, cells activate a multipronged DNA damage response. This response encompasses repair of the lesions that stall RNA polymerase (RNAP) but also a poorly understood, genome-wide shutdown of transcription, even o...

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Detalles Bibliográficos
Autores principales: Gregersen, Lea H., Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929563/
https://www.ncbi.nlm.nih.gov/pubmed/29699641
http://dx.doi.org/10.1016/j.tibs.2018.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929563/
https://www.ncbi.nlm.nih.gov/pubmed/29699641
http://dx.doi.org/10.1016/j.tibs.2018.02.010

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