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The Cellular Response to Transcription-Blocking DNA Damage
In response to transcription-blocking DNA lesions such as those generated by UV irradiation, cells activate a multipronged DNA damage response. This response encompasses repair of the lesions that stall RNA polymerase (RNAP) but also a poorly understood, genome-wide shutdown of transcription, even o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Trends Journals
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929563/ https://www.ncbi.nlm.nih.gov/pubmed/29699641 http://dx.doi.org/10.1016/j.tibs.2018.02.010 |