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Optimal dynamic control approach in a multi-objective therapeutic scenario: Application to drug delivery in the treatment of prostate cancer

Numerous problems encountered in computational biology can be formulated as optimization problems. In this context, optimization of drug release characteristics or dosing schedules for anticancer agents has become a prominent area not only for the development of new drugs, but also for established d...

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Detalles Bibliográficos
Autores principales: Irurzun-Arana, Itziar, Janda, Alvaro, Ardanza-Trevijano, Sergio, Trocóniz, Iñaki F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929575/
https://www.ncbi.nlm.nih.gov/pubmed/29672523
http://dx.doi.org/10.1371/journal.pcbi.1006087