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Combining a Toggle Switch and a Repressilator within the AC-DC Circuit Generates Distinct Dynamical Behaviors

Although the structure of a genetically encoded regulatory circuit is an important determinant of its function, the relationship between circuit topology and the dynamical behaviors it can exhibit is not well understood. Here, we explore the range of behaviors available to the AC-DC circuit. This ci...

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Detalles Bibliográficos
Autores principales: Perez-Carrasco, Ruben, Barnes, Chris P., Schaerli, Yolanda, Isalan, Mark, Briscoe, James, Page, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929911/
https://www.ncbi.nlm.nih.gov/pubmed/29574056
http://dx.doi.org/10.1016/j.cels.2018.02.008