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Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein–Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis

The biosynthesis of small-size polyene macrolides is ultimately controlled by a couple of transcriptional regulators that act in a hierarchical way. A Streptomyces antibiotic regulatory protein–large ATP-binding regulator of the LuxR family (SARP-LAL) regulator binds the promoter of a PAS-LuxR regul...

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Detalles Bibliográficos
Autores principales: Barreales, Eva G., Vicente, Cláudia M., de Pedro, Antonio, Santos-Aberturas, Javier, Aparicio, Jesús F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930380/
https://www.ncbi.nlm.nih.gov/pubmed/29500267
http://dx.doi.org/10.1128/AEM.00246-18