Cargando…

Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein–Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis

The biosynthesis of small-size polyene macrolides is ultimately controlled by a couple of transcriptional regulators that act in a hierarchical way. A Streptomyces antibiotic regulatory protein–large ATP-binding regulator of the LuxR family (SARP-LAL) regulator binds the promoter of a PAS-LuxR regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barreales, Eva G., Vicente, Cláudia M., de Pedro, Antonio, Santos-Aberturas, Javier, Aparicio, Jesús F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Genetics and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930380/ https://www.ncbi.nlm.nih.gov/pubmed/29500267 http://dx.doi.org/10.1128/AEM.00246-18

Ejemplares similares

Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis
por: Martínez-Burgo, Yolanda, et al.
Publicado: (2019)

Effect of PAS-LuxR Family Regulators on the Secondary Metabolism of Streptomyces
por: Zhang, Naifan, et al.
Publicado: (2022)

LAL Regulators SCO0877 and SCO7173 as Pleiotropic Modulators of Phosphate Starvation Response and Actinorhodin Biosynthesis in Streptomyces coelicolor
por: Guerra, Susana M., et al.
Publicado: (2012)

Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF
por: Vicente, Cláudia M., et al.
Publicado: (2022)

LuxR-Type SCO6993 Negatively Regulates Antibiotic Production at the Transcriptional Stage by Binding to Promoters of Pathway-Specific Regulatory Genes in Streptomyces coelicolor
por: Tsevelkhoroloo, Maral, et al.
Publicado: (2022)

Regulation of Coronafacoyl Phytotoxin Production by the PAS-LuxR Family Regulator CfaR in the Common Scab Pathogen Streptomyces scabies
por: Cheng, Zhenlong, et al.
Publicado: (2015)

PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis
por: Vicente, Cláudia M, et al.
Publicado: (2009)

A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in Streptomyces hygrospinosus var. beijingensis
por: Shen, Jufang, et al.
Publicado: (2019)

β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593
por: Panthee, Suresh, et al.
Publicado: (2020)

Production of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027
por: Li, Xingxing, et al.
Publicado: (2022)

Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors
por: Brameyer, Sophie, et al.
Publicado: (2015)

LuxR solos in Photorhabdus species
por: Brameyer, Sophie, et al.
Publicado: (2014)

Microbial Primer: LuxR-LuxI Quorum Sensing
por: Soto-Aceves, Martin P., et al.
Publicado: (2023)

Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in Streptomyces piomogeues var. Hangzhouwanensis
por: Li, Yan, et al.
Publicado: (2018)

Hierarchical Control on Polyene Macrolide Biosynthesis: PimR Modulates Pimaricin Production via the PAS-LuxR Transcriptional Activator PimM
por: Santos-Aberturas, Javier, et al.
Publicado: (2012)

Chimeric LuxR Transcription Factors Rewire Natural Product Regulation
por: Mukherji, Ruchira, et al.
Publicado: (2020)

Genomic characterization of bacteria from the ultra-oligotrophic Madison aquifer: insight into the archetypical LuxI/LuxR and identification of novel LuxR solos
por: Wengert, Peter C., et al.
Publicado: (2021)

Studies on synthetic LuxR solo hybrids
por: Passos da Silva, Daniel, et al.
Publicado: (2015)

Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives
por: Payero, Tamara D, et al.
Publicado: (2015)

A Walk into the LuxR Regulators of Actinobacteria: Phylogenomic Distribution and Functional Diversity
por: Santos, Catarina Lopes, et al.
Publicado: (2012)

Streptomyces natalensis programmed cell death and morphological differentiation are dependent on oxidative stress
por: Beites, Tiago, et al.
Publicado: (2015)

Census of solo LuxR genes in prokaryotic genomes
por: Hudaiberdiev, Sanjarbek, et al.
Publicado: (2015)

LuxR Solos from Environmental Fluorescent Pseudomonads
por: Bez, Cristina, et al.
Publicado: (2021)

Uncovering the Cryptic Gene Cluster ahb for 3-amino-4-hydroxybenzoate Derived Ahbamycins, by Searching SARP Regulator Encoding Genes in the Streptomyces argillaceus Genome
por: Ye, Suhui, et al.
Publicado: (2023)

Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR
por: Brackman, Gilles, et al.
Publicado: (2008)

2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation
por: Li, Sizhe, et al.
Publicado: (2017)

Identification of LuxR Family Regulators That Integrate Into Quorum Sensing Circuit in Vibrio parahaemolyticus
por: Zhong, Xiaojun, et al.
Publicado: (2021)

The LuxI/LuxR-Type Quorum Sensing System Regulates Degradation of Polycyclic Aromatic Hydrocarbons via Two Mechanisms
por: Yu, Zhiliang, et al.
Publicado: (2020)

luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria
por: Brotherton, Carolyn A., et al.
Publicado: (2018)

A bioinformatic survey of distribution, conservation, and probable functions of LuxR solo regulators in bacteria
por: Subramoni, Sujatha, et al.
Publicado: (2015)

Streptomyces smaragdinus sp. nov., isolated from the gut of the fungus growing-termite Macrotermes natalensis
por: Schwitalla, Jan W., et al.
Publicado: (2020)

LuxR402 of Novosphingobium sp. HR1a regulates the correct configuration of cell envelopes
por: Segura, Ana, et al.
Publicado: (2023)

The LuxR Regulators PcoR and RfiA Co-regulate Antimicrobial Peptide and Alginate Production in Pseudomonas corrugata
por: Licciardello, Grazia, et al.
Publicado: (2018)

In silico analyses of conservational, functional and phylogenetic distribution of the LuxI and LuxR homologs in Gram-positive bacteria
por: Rajput, Akanksha, et al.
Publicado: (2017)

Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression
por: Zhang, Jun, et al.
Publicado: (2021)

PpoR is a conserved unpaired LuxR solo of Pseudomonas putida which binds N-acyl homoserine lactones
por: Subramoni, Sujatha, et al.
Publicado: (2009)

The Streptomyces filipinensis Gamma-Butyrolactone System Reveals Novel Clues for Understanding the Control of Secondary Metabolism
por: Barreales, Eva G., et al.
Publicado: (2020)

PcsR2 Is a LuxR-Type Regulator That Is Upregulated on Wheat Roots and Is Unique to Pseudomonas chlororaphis
por: Pan, Huiqiao, et al.
Publicado: (2020)

Mechanism Underlying the Role of LuxR Family Transcriptional Regulator abaR in Biofilm Formation by Acinetobacter baumannii
por: Sun, Xu, et al.
Publicado: (2021)

Modeling Analysis of Signal Sensitivity and Specificity by Vibrio fischeri LuxR Variants
por: Colton, Deanna M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_umf40gnomrfgoip83djutevm9q