FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map

Recent sequencing technologies enable joint quantification of promoters and their enhancer regions, allowing inference of enhancer–promoter links. We show that current enhancer–promoter inference methods produce a high rate of false positive links. We introduce FOCS, a new inference method, and by b...

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Detalles Bibliográficos
Autores principales: Hait, Tom Aharon, Amar, David, Shamir, Ron, Elkon, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930446/
https://www.ncbi.nlm.nih.gov/pubmed/29716618
http://dx.doi.org/10.1186/s13059-018-1432-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930446/
https://www.ncbi.nlm.nih.gov/pubmed/29716618
http://dx.doi.org/10.1186/s13059-018-1432-2

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