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FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map
Recent sequencing technologies enable joint quantification of promoters and their enhancer regions, allowing inference of enhancer–promoter links. We show that current enhancer–promoter inference methods produce a high rate of false positive links. We introduce FOCS, a new inference method, and by b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930446/ https://www.ncbi.nlm.nih.gov/pubmed/29716618 http://dx.doi.org/10.1186/s13059-018-1432-2 |