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Transcription Factor Co-expression Networks of Adipose RNA-Seq Data Reveal Regulatory Mechanisms of Obesity

BACKGROUND: Transcription Factors (TFs) control actuation of genes in the genome and are key mediators of complex processes such as obesity. Master Regulators (MRs) are the genes at the top of a regulation hierarchy which regulate other genes. OBJECTIVE: To elucidate clusters of highly co-expressed...

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Detalles Bibliográficos
Autores principales: Skinkyte-Juskiene, Ruta, Kogelman, Lisette J.A., Kadarmideen, Haja N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930450/
https://www.ncbi.nlm.nih.gov/pubmed/29755291
http://dx.doi.org/10.2174/1389202918666171005095059