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Role of Sequence Variations in AhR Gene Towards Modulating Smoking Induced Lung Cancer Susceptibility in North Indian Population: A Multiple Interaction Analysis

BACKGROUND: AhR, a ubiquitously expressed ligand-activated transcription factor, upon its encounter with the foreign ligands activates the transcriptional machinery of genes encoding for bio-transformation enzymes like CYP1A1 hence, mediating the metabolism of Poly aromatic hydrocarbons and nitrosam...

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Detalles Bibliográficos
Autores principales: Budhwar, Sneha, Bahl, Charu, Sharma, Siddharth, Singh, Navneet, Behera, Digambar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930452/
https://www.ncbi.nlm.nih.gov/pubmed/29755293
http://dx.doi.org/10.2174/1389202918666170915160606