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Lipopolysaccharide Mediates the Destruction of Intercellular Tight Junction among Renal Tubular Epithelial Cells via RhoT1/SMAD-4/JAM-3 Pathway

Background: The morbidity of sepsis induced acute kidney injury remains unacceptable high and the mechanisms of that disease remains unclear. For urine backleak and intercellular tight junction among tubular epithelial cells (TECs) destruction often occur during sepsis induced acute kidney injury, w...

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Detalles Bibliográficos
Autores principales: Zheng, Shixiang, Lin, Zhuoyong, Liu, Zhongwei, Liu, Yipeng, Wu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930461/
https://www.ncbi.nlm.nih.gov/pubmed/29725250
http://dx.doi.org/10.7150/ijms.23786