Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart

RNA binding motif 20 (RBM20) regulates pre-mRNA splicing of over thirty genes, among which titin is a major target. With RBM20 expression, titin expresses a larger isoform at fetal stage to a smaller isoform at adult resulting from alternative splicing, while, without RBM20, titin expresses exclusiv...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhu, Chaoqun, Yin, Zhiyong, Wang, Qiurong, Sun, Mingming, Cao, Huojun, Greaser, Marion L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930469/
https://www.ncbi.nlm.nih.gov/pubmed/29725258
http://dx.doi.org/10.7150/ijbs.24117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930469/
https://www.ncbi.nlm.nih.gov/pubmed/29725258
http://dx.doi.org/10.7150/ijbs.24117

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