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Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart

RNA binding motif 20 (RBM20) regulates pre-mRNA splicing of over thirty genes, among which titin is a major target. With RBM20 expression, titin expresses a larger isoform at fetal stage to a smaller isoform at adult resulting from alternative splicing, while, without RBM20, titin expresses exclusiv...

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Detalles Bibliográficos
Autores principales:	Guo, Wei, Zhu, Chaoqun, Yin, Zhiyong, Wang, Qiurong, Sun, Mingming, Cao, Huojun, Greaser, Marion L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930469/ https://www.ncbi.nlm.nih.gov/pubmed/29725258 http://dx.doi.org/10.7150/ijbs.24117

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