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Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing

In recent years, while the use of the clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated protein 9 (Cas9) (CRISPR-Cas9) system for targeted genome editing has become a research hotspot, it has, to date, not proved adequate for genome editing in large mammals, such as...

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Detalles Bibliográficos
Autores principales: Hao, Fei, Yan, Wei, Li, Xiaocong, Wang, Hui, Wang, Yingmin, Hu, Xiao, Liu, Xu, Liang, Hao, Liu, Dongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930475/
https://www.ncbi.nlm.nih.gov/pubmed/29725264
http://dx.doi.org/10.7150/ijbs.23890