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Repair of Critical-Sized Mandible Defects in Aged Rat Using Hypoxia Preconditioned BMSCs with Up-regulation of Hif-1α

The repair of bone defects in the geriatric population remains a challenge for modern medicine. Transplantation of bone marrow mesenchymal stem cells (BMSCs) combined with or without biomaterials has been a promising approach to bone restoration and regeneration. Typically, the transplanted BMSCs ar...

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Detalles Bibliográficos
Autores principales: Zhang, Jiankang, Feng, Zhuozhuo, Wei, Junjun, Yu, Yunbo, Luo, Jie, Zhou, Jing, Li, Yi, Zheng, Xiaohui, Tang, Wei, Liu, Lei, Long, Jie, Li, Xiaoyu, Jing, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930477/
https://www.ncbi.nlm.nih.gov/pubmed/29725266
http://dx.doi.org/10.7150/ijbs.24158