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MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

BACKGROUND: The granulosa cells are indispensable for follicular development and its function is orchestrated by several genes, which in turn posttranscriptionally regulated by microRNAs (miRNA). In our previous study, the miRRNA-424/503 cluster was found to be highly abundant in bovine granulosa ce...

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Detalles Bibliográficos
Autores principales: Pande, Hari Om, Tesfaye, Dawit, Hoelker, Michael, Gebremedhn, Samuel, Held, Eva, Neuhoff, Christiane, Tholen, Ernst, Schellander, Karl, Wondim, Dessie Salilew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930509/
https://www.ncbi.nlm.nih.gov/pubmed/29716627
http://dx.doi.org/10.1186/s13048-018-0410-3