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Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

BACKGROUND: The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response,...

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Detalles Bibliográficos
Autores principales: Steinaa, Lucilla, Svitek, Nicholas, Awino, Elias, Njoroge, Thomas, Saya, Rosemary, Morrison, Ivan, Toye, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930519/
https://www.ncbi.nlm.nih.gov/pubmed/29716583
http://dx.doi.org/10.1186/s12917-018-1460-x