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PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. However, the precise mechanism of action of PCNP in the process of tumor growth has not yet been fully elucidated. METHODS: ShRNA knockdown and overexpression of PCNP wer...

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Detalles Bibliográficos
Autores principales: Wu, Dong-Dong, Gao, Ying-Ran, Li, Tao, Wang, Da-Yong, Lu, Dan, Liu, Shi-Yu, Hong, Ya, Ning, Hui-Bin, Liu, Jun-Ping, Shang, Jia, Shi, Jun-Feng, Wei, Jian-She, Ji, Xin-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930684/
https://www.ncbi.nlm.nih.gov/pubmed/29716528
http://dx.doi.org/10.1186/s12885-018-4391-9