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Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition

BACKGROUND: Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the in vitro anticancer and P-glycoprotein inhibitory potential of extracts of...

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Detalles Bibliográficos
Autores principales: Burger, Trevor, Mokoka, Tsholofelo, Fouché, Gerda, Steenkamp, Paul, Steenkamp, Vanessa, Cordier, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930800/
https://www.ncbi.nlm.nih.gov/pubmed/29720141
http://dx.doi.org/10.1186/s12906-018-2208-7