Concise synthesis of artemisinin from a farnesyl diphosphate analogue

Artemisinin is one of the most potent anti-malaria drugs and many often-lengthy routes have been developed for its synthesis. Amorphadiene synthase, a key enzyme in the biosynthetic pathway of artemisinin, is able to convert an oxygenated farnesyl diphosphate analogue directly to dihydroartemisinic...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoping, Demiray, Melodi, Wirth, Thomas, Allemann, Rudolf K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930831/
https://www.ncbi.nlm.nih.gov/pubmed/28404524
http://dx.doi.org/10.1016/j.bmc.2017.03.068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930831/
https://www.ncbi.nlm.nih.gov/pubmed/28404524
http://dx.doi.org/10.1016/j.bmc.2017.03.068

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