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NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells

BACKGROUND: NKX2.5 is a transcription factor transiently expressed during thyroid organogenesis. Recently, several works have pointed out the oncogenic role of NKX2.5 in a variety of tumors. We therefore hypothesized that NKX2.5 could also play a role in thyroid cancer. METHODS: The validation of NK...

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Detalles Bibliográficos
Autores principales: Penha, Ricardo Cortez Cardoso, Buexm, Luisa Aguirre, Rodrigues, Fabiana Resende, de Castro, Taciana Padilha, Santos, Maria Carolina S., Fortunato, Rodrigo Soares, Carvalho, Denise P., Cardoso-Weide, Luciene C., Ferreira, Andrea C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930850/
https://www.ncbi.nlm.nih.gov/pubmed/29716526
http://dx.doi.org/10.1186/s12885-018-4399-1