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The t(14;18) translocation is absent from endothelial and follicular dendritic cells of follicular lymphoma (FL) and shows heterogeneous presence in preserved FL mantle zones

BACKGROUND: The translocation t(14;18)(q32;q21) is the genetic hallmark of follicular lymphoma (FL) and can be observed in 85–90% of cases. Whether the translocation is restricted to cells with germinal center B-cell phenotype or can be observed in other cell types of the microenvironment remains de...

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Detalles Bibliográficos
Autores principales: Kosmidis, Perikles, Mankel, Barbara, Fend, Falko, Adam, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930855/
https://www.ncbi.nlm.nih.gov/pubmed/29720207
http://dx.doi.org/10.1186/s13000-018-0703-2